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The oil

What is CBD?

CBD (cannabidiol) is one of the well-known cannabinoids found in the hemp plant. While THC (tetrahydrocannabinol) is the main psychoactive cannabinoid that makes you ‘high’, CBD doesn’t have this effect, and is used to support the mind and body.

What is CBG?

CBG (cannabigerol) is one of the well-known cannabinoids found in higher concentrations of the hemp plant. It starts out as an acidic-based cannabinoid, CBGA (cannabigerolic acid), and synthesises into others like THCA, CBDA and CBCA. Then through heat and sunlight, the acid burns off and the cannabinoids synthesise into THC, CBD, CBG, CBC, CBN or THCY. Without CBGA, none of these well-known cannabinoids would exist, which is why it’s known as ‘the mother of all cannabinoids’.

CBG is extracted in the early stages of flowering of the hemp plant (sixth and the eighth week), as this is when its concentrations are the highest and best quality – right before it develops into other substances.

Why do you mix your products with MCT oil?

Because CBD is fat-soluble, it works best when you take it with saturated fats like MCT oil, helping larger concentrations reach and be absorbed by your bloodstream – giving you better results. The MCT carrier oil we use in our products is derived from coconuts, and is believed to help with weight loss, memory function, athletes’ energy and ketosis. Studies are also looking into whether the oil helps with Alzheimer’s disease, autism, type 2 diabetes and specific types of epilepsy.

What does broad spectrum mean?

At Puregenics, all our products are ‘broad spectrum’, which means they have the full spectrum of extracted cannabinoids and terpenes, but all THC has been removed through CO2 extraction. Check out our lab results to find out what’s in every drop.

What is third-party lab testing?

Third-party/independent laboratory reports are also known as a ‘certificate of analysis’. It’s a document that shows the breakdown, composition and compounds in CBD product samples sent for analysis to an independent, certified cannabis-testing lab. In a nutshell, it tells you whether the product is what it’s advertised to be.

At Puregenics, our concentrated oil is shipped to the UK from Europe to be processed, bottled and third-party tested. Following the guidelines on CBD drops, each batch has their own lab reports, which can be traced back to its first point of manufacturing.

Each report shows the concentration of cannabinoids and makes sure our products are free from any heavy metals, mould, mildew, fungus, yeast, E. coli, salmonella and mycotoxins. Because we don’t remove or add any compounds to our products, terpenes vary with every plant, even under strict growing conditions, but we make sure 100% of all THC has been removed through CO2 extraction.

What is IFOAM – Organics International?

Puregenics is a member of IFOAM – Organics International. They encourage an organic, ethical and sustainable way of working to agriculture around the world.

How to use

How much CBD do I take?

Everyone is different, so the correct dosage can depend on the person, their body weight, metabolism, body chemistry and the CBD oil strength they’ve chosen.

Depending on which Puregenics product you’re taking, each bottle has a different suggested serving guide, which you’ll find on our product pages in the ‘How to use’ section, and on every product that’s delivered to your door. But overall, the FSA recommends no more than 70mg per day. It’s also been suggested you should use your body weight as a guide, where you have 1mg to 6mg per 4.5kg of your body weight.

We always suggest you start slowly, with a small intake of CBD daily. If you have any adverse symptoms when taking your CBD, we recommend you reduce your dosage and increase it again slowly until you find your optimal dose.

Do I take the same daily dose as I did with my last CBD product?

Even if you’re using a similar product, we always recommend you compare the ingredients to ours beforehand. A lot of CBD companies use flavourings, which can compromise the amount of CBD. At Puregenics, we only use CBD and MCT oil in our products to keep it as natural as possible, so it may have a higher CBD concentration compared to what you were last using.

What's the best way to take CBD oil?

How you take your CBD is crucial, as it affects how much can be absorbed by your bloodstream. To get the most effective results, we recommend you use the pipette, drop the oil under your tongue and keep it there for 90 seconds before swallowing. By putting the CBD under your tongue, it has a more direct route into your bloodstream, as it’s soaked up into your system quicker through your mucus membranes.

Who should not use CBD oil?

CBD products could possibly be unsafe, and should NOT be taken by people who are pregnant, breastfeeding or 18 and under – especially children. It’s important to note that if you’ve had/you have an allergy to coconuts, coconut oil, MCT (medium chain triglyceride) or any other part of MCT oil – Puregenics products contain MCT oil.

How it works

How does CBD work with your body?

Once in your bloodstream, CBD can interact with cells in your body in many ways – more specifically, the ‘cannabinoid receptors’, which sit on the surface of your cells and make up the ‘endocannabinoid system’. While experts are still exploring the function of the endocannabinoid system, it’s said to bring balance to our tissues, including the heart, digestive, endocrine, immune, nervous, and reproductive systems.

The endocannabinoid system receptors come in multiple shapes and sizes, which bind and respond differently to cannabinoids from the cannabis plant. Out of these different shapes and sizes, there are two prominent types called ‘CB1’ and ‘CB2’. CB1 receptors tend to be in the central nervous system, while CB2 receptors tend to be outside the central nervous system.

What side effects can you get from CBD?

While CBD oil side effects are rare, you can get some adverse side effects if you take too much or haven’t found the right dosage for you. You could experience things like diarrhea, appetite changes, low blood pressure, a dry mouth, nausea, fatigue and possible weight changes.

Can CBD oil interact with medication?

One of the most important things to do before taking CBD is to find out if it could interact with any medication you’re taking. We always recommend you talk to your doctor about how much CBD you should be taking or if you have any questions, as it can cause some slight risks if you use CBD in high doses or for an extended amount of time.

While side effects aren’t necessarily common, not talking to your doctor could put you at risk of mild, low blood pressure, dry mouth, light-headedness, sedation, decreased fertilisation capacity, as well as reduced activity of T and B cells, P-glycoprotein and cytochrome CYP450 enzymes.

Can CBD affect our cytochrome CYP450 enzymes?

Although it isn’t common for CBD to cause many side effects, cannabinoids can affect the liver’s cytochrome CYP450 enzyme function. Something like grapefruit juice can cause the same problem.

Around 60% of all pharmaceutical drugs go through this chemical process by this enzyme, including, but not limited to: steroids, HMG-CoA reductase inhibitors, calcium channel blockers, antihistamines, prokinetics, HIV antivirals, immune modulators, benzodiazepines, anti-arrhythmics, antibiotics, anaesthetics, antipsychotics, antidepressants, anti-epileptics, beta blockers, PPIs, NSAIDs, angiotensin-2 receptor blockers, oral hypoglycemic agents and sulfonylureas.